April 9, 2018

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CLOSURES AND SUSPENSIONS
GYNECOLOGIC
GOG-0281: Reminder! Closure to registrations on April 10, 2018 at 5:00PM ET.

GOG Legacy Terminations
GOG-0184: Terminated January 27, 2018; version date: January 12, 2004 (posted on GOG).
GOG-0186H: Terminated January 27, 2018; version date: July 7, 2016 (posted on NRG Oncology).
GOG-0186J: Terminated January 27, 2018; version date: March 9, 2015 (posted on GOG).
GOG-0220: Terminated January 27, 2018; version date: December 17, 2014 (posted on GOG).
GOG-0227G: Terminated January 27, 2018; version date: December 17, 2014 (posted on GOG).
GOG-0247: Terminated January 27, 2018; version date: October 18, 2011 (posted on GOG).
GOG-0256: Terminated January 27, 2018; version date: May 11, 2011 (posted on GOG).
GOG-0271: Terminated January 27, 2018; version date: May 5, 2011 (posted on GOG).
GOG-0280: Terminated January 27, 2018; version date: May 2, 2016 (posted on NRG Oncology).
GOG-9924: Terminated January 27, 2018; version date: March 20, 2013 (posted on NRG Oncology).
GOG-9928: Terminated January 27, 2018; version date: August 19, 2013 (posted on NRG Oncology).

AMENDMENTS AND UPDATES
GYNECOLOGIC
GOG-0225: Amendment 7; version date: March 23, 2018 (posted on NRG Oncology).

GOG-0277: Amendment 3; version date: December 7, 2017 (posted on CTSU).

FORM UPDATES
HEAD & NECK
NRG-HN003 CORRECTION: Specimen Transmittal form (For Peripheral Blood, version date March 20, 2018) is available on the  NRG website not the CTSU website as stated on the March 26th Broadcast.

OTHER PROTOCOL NOTICES
1. Alliance N1048 Prospect Trial – Accrual Update: "A phase II/III trial of neoadjuvant FOLFOX with selective use of combined modality chemoradiation versus preoperative combined modality chemoradiation for locally advanced rectal cancer patients undergoing low anterior resection with total mesorectal excision" is open to accrual for patients with locally advanced rectal cancer who are candidates for a TME. Christopher Crane, MD, and Thomas George, MD, are the NCTN Group Co-Chairs for NRG Oncology. As of April 6, 2018, a total of 1,002 patients have been enrolled on the trial and only 118 more are needed to complete accrual. Please consider enrolling your eligible patients to this important study. Enrollment credited to NRG Oncology will count towards membership requirements.

2. BREAST
NSABP B-55/BIG 6-13: Reminder! Sample Size Increase (posted to CTSU).

3. GYNECOLOGIC
GOG-9923 Legacy Protocol: Data Management Responsibility Transition Memo (posted on GOG).

3. VTOC Training
The VTOC Webinar Training Series schedule and registration is available for NRG Oncology Research Associates working on RTOG 0924, RTOG 0920, NRG-HN001, NRG-HN002, NRG-CC003, and NRG-CC004. Space is limited so register now and reserve your seat.  The next webinar training is scheduled for April 11, 2018.

DRUG SAFETY UPDATES
Safety updates have been issued for NSABP legacy studies.  For details, please see the NSABP E-mail Distributions page and CTSU.

Safety updates have been issued for the following studies:
- Cabozantinib: NRG-GY001
- Ipilimumab: NRG-BN002, NRG-GY003
- Nivolumab: NRG-BN002, NRG-GY002, NRG-GY003 

  • For NRG-GY001 safety reports, please see CTSU.
  • For NRG-BN002, NRG-GY002, and NRG-GY003 safety reports, please see the protocol page on  NRG Oncology.

 

PUBLICATIONS REMINDERS
NRG Oncology is pleased to report the scientific articles and abstracts that have appeared or have been presented during the previous week. This publications report includes links, when available, to the article, PubMed abstract, or association abstract.


JOURNAL ARTICLES
Abrunhosa-Branquinho AN, Bar-Deroma R, Collette S, Clementel E, Liu Y, Hurkmans CW, Feuvret L, Van Beek K, van den Bent M, Baumert BG, Weber DC. Radiotherapy quality assurance for the RTOG 0834/EORTC 26053-22054/NCIC CTG CEC.1/CATNON intergroup trial "concurrent and adjuvant temozolomide chemotherapy in newly diagnosed non-1p/19q deleted anaplastic glioma": Individual case review analysis. Radiother Oncol. 2018 Mar 29. pii: S0167-8140(18)30145-2. doi: 10.1016/j.radonc.2018.03.013. [Epub ahead of print] PubMed PMID: 29606522. Read more

Small W Jr, James JL, Moore TD, Fintel DJ, Lutz ST, Movsas B, Suntharalingam M, Garces YI, Ivker R, Moulder J, Pugh S, Berk LB. Utility of the ACE Inhibitor Captopril in Mitigating Radiation associated Pulmonary Toxicity in Lung Cancer: Results From NRG Oncology RTOG 0123. Am J Clin Oncol. 2018 Apr;41(4):396-401. doi: 10.1097/COC.0000000000000289. PubMed PMID: 27100959; PubMed Central PMCID:PMC5073047.  Read more

PUBLICATIONS REMINDERS
Please note the following upcoming meeting and abstract submission deadline dates

Upcoming Meetings
American Association for Cancer Research (AACR); Apr 14-18, 2018; Chicago, IL
American Association of Neurological Surgeons (AANS); Apr 28 - May 2, 2018 New Orleans, LA
American Association for Thoracic Surgery (AATS); Apr 28 - May 1, 2018; San Diego, CA
American Head & Neck Society (AHNS); Apr 18-19, 2018; National Harbor, MD
American Radium Society (ARS); May 5-8, 2018; Orlando, FL
American Society of Breast Surgeons (ASBS); May 2-6, 2018; Orlando, FL
European Society for Radiotherapy and Oncology (ESTRO);Apr 20-24, 2018; Barcelona, Spain

Upcoming Abstract Submission Deadlines
American Society for Radiation Oncology (ASTRO); Oct 21-24, 2018; San Antonio, TX; Late-breaking Aug 1, 2018
European Society for Medical Oncology (ESMO); Oct 19-23, 2018; Munich, Germany; due to publications committee Apr 25, 2018; meeting abstracts submission deadline May 9, 2018; Late-breaking Sep 17, 2018
International Society for Quality of Life Research (ISOQOL); Oct 24-27, 2018; Dublin, Ireland; meeting abstracts submission deadline Apr 16, 2018
Multinational Association of Supportive Care in Cancer (MASCC); Jun 28-30, 2018; Vienna, Austria; Late-breaking due Apr 22, 2018 

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